|
KMID : 1059520120560030328
|
|
Journal of the Korean Chemical Society
2012 Volume.56 No. 3 p.328 ~ p.333
|
|
|
Ultrasound Mediated, Sodium Bisulfite Catalyzed, Solvent Free Synthesis of 6-Amino-3-methyl-4-substitued-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
|
|
Darandale Sunil N.
Sangshetti Jaiprakash N.
Shinde Devanand B.
|
|
|
Abstract
|
|
|
|
A simple, convenient and practical green synthetic protocol for sodium bisulfite catalyzed multicomponent reaction of ethyl acetoacetate, hydrazine hydrate, malononitrile, and various aldehydes for the synthesis of 6-amino-4-phenyl- 3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles using ultrasound irradiations in solvent free condition. This method provides the advantage of operational simplicity, shorter reaction time and excellent yields making the protocol environment friendly and economically lucrative.
|
|
|
KEYWORD
|
|
|
Pyrano[2,3-c]pyrazole, Substituted aldehydes, Sodium bisulfite catalyst
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|